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We are thrilled to announce that Mike Blum has joined Ambit as our new Executive Vice President (EVP). Mike is a seasoned leader, with 30 years of experience in rare disease and biologics, where he has consistently driven success through his strategic vision and deep understanding of commercial operations. With a proven track record of launching life-changing therapies and building high-performing teams, Mike’s expertise will be instrumental as Ambit continues to expand its impact in the rare disease space and beyond.

A Proven Leader in Rare Disease and Biologics

Mike’s career is marked by his exceptional leadership in launching and commercializing groundbreaking therapies. He has played pivotal roles in the development and launch of multiple rare disease treatments, including those for Duchenne muscular dystrophy (DMD), Gaucher disease, mucopolysaccharidosis type II (MPS II), and hereditary angioedema (HAE). His experience spans sales, marketing, market access, and patient support services, all of which have been critical in ensuring patients receive the therapies they need as quickly as possible.

In his most recent position, Mike served as the Chief Commercial Officer at Homology Medicines, Inc. For the last 5 years, Mike’s efforts have been directed at Commercial strategies to deliver one-time gene therapy and gene editing technologies to rare disease patients. Before joining Homology, Mike was the Head of Commercial Operations at Zafgen, Inc., where he was responsible for the commercial strategy across rare diseases and other treatment areas. He also held leadership positions at Sarepta Therapeutics and Shire Pharmaceuticals, where he successfully led the launches of orphan drug treatments such as ELAPRASE®, VPRIV®, and FIRAZYR®.

Reflecting on his career, Mike shared, “I’ve always been passionate about finding innovative ways to help patients access life-changing therapies. The work I’ve done across a number of rare disease areas has shown me the power of novel treatments to transform lives.” 

Leveraging Experience to Drive Success at Ambit

In his new role at Ambit, Mike will leverage his broad therapeutic experience and deep understanding of commercial strategy to help our clients overcome challenges and seize new opportunities. His unique perspective, honed through leadership roles in four different start-up commercial organizations, positions him to make a significant impact on our clients and their success.

“Ambit’s commitment to its clients and its fast-paced, client-first culture are what drew me to the company,” Mike said. “I’m excited to work with a team of experts who consistently exceed expectations and deliver outstanding results.”

Ambit Chief Commercial Officer, Ned Kitfield said, "We are incredibly excited to welcome Mike to the Ambit team. Mike's extensive experience in the rare disease and biologics sectors, combined with his proven ability to lead successful product launches, makes him an invaluable addition to our organization. His strategic insight and passion for improving patient outcomes align perfectly with our mission at Ambit. I’ve known Mike for years and have no doubt that he will play a pivotal role in helping us expand our impact and continue delivering exceptional results for our clients." 

A Passion for Boston Sports and Family Time

Outside of work, Mike is an avid Boston sports enthusiast. His family's love for sports runs deep, and they've turned his son's football games into cherished weekend gatherings, where they come together to support the team and enjoy quality time with one another. Whether attending a football game or cheering for a Boston team at any sporting event, Mike treasures these moments spent with family, united by their shared passion for sports.

We’re thrilled to have Mike on Team Ambit and look forward to the positive impact he has in store for the organization!